Step 1: ProBurn Advanced
(Burn Calories) | 60 Capsules

Step 1: ProBurn Advanced (Burn Calories) by PC Laboratories

Step 1 of our PC Laboratories 3 Step Fat Loss System is all about Burning Calories and making your weight loss journey easier. Whether it be improving your energy levels, reducing hunger or helping you avoid the “diet-brain”, ProBurn can help to make your weight loss journey easier to manage and your nutrition/training programs easier to stick to. ProBurn focuses on 4 different pathways to help you achieve your weight loss goal in a healthy and efficient way.

Burn Calories

At its very core weight loss comes down to a simple equation of Calories In vs. Calories Out. A small increase in your Daily Metabolic Rate may seem minor but can make a huge difference. Let us explain, for example;

• Fiona is following a tailored nutrition and training program and is estimated to be in a 200 calorie deficit.
• Fiona Introduces ProBurn Advanced and starts burning an additional 100 calories per day by increasing her metabolism and thermogenesis through ProBurn.
• Plus thanks to ProBurn Fiona has more energy and focus during the day so she is naturally more active and exercising with more intensity, increasing her daily calorie burn by another 100 calories.
• Fiona has now successfully taken her calorie deficit from 200 calories daily to 400 calories daily which in effect has doubled her fat-burning potential for that day.

Increase Energy with No Crash! 

During a calorie deficit, your body tends to conserve energy which can cause periods where you feel tired or lethargic. ProBurn contains a moderate amount of clinically trialled and proven ingredients that will help to increase your energy within 20-30 minutes. These ingredients include Caffeine, Hordenine and Synephrine, by introducing these stimulants ProBurn is able to deliver clean, steady energy, focus and motivation without overstimulation or the feeling of “the jitters”. Additionally, ProBurn includes Alpha GPC and Griffonia Simplicifolia Extract which work to support your natural Serotonin and Dopamine production which helps to eliminate crash.

The dosage protocol of ProBurn is to take 1 capsule in the morning on an empty stomach to kickstart your metabolism and give you energy in the morning. We recommend taking your second serve in the early afternoon or just before training. This will ensure you have energy all day long, and/or for your exercise so you can train more intensely. To ensure there is no disturbance to your sleeping patterns we recommend taking your second dose of ProBurn no later than 5 pm.

Appetite & Craving Control

A sustained calorie deficit for fat loss can have interesting impacts on our body’s signalling system and hormone levels. During your weight loss journey, you will likely feel hunger on a daily basis and may even experience cravings. Cravings during a calorie deficit are commonly for sweet, salty or carbohydrate-dense foods. These are foods that your body might want for the “fast energy” they can provide as well as the dopamine/serotonin hit they provide to the diet-depleted pleasure centres of your brain.
ProBurn includes Alpha GPC and Griffonia Simplicifolia Extract which support dopamine/serotonin production and will help to reduce cravings. Ingredients such as Caffeine and Capsacian have been scientifically shown to reduce hunger. ProBurn’s ingredients should make sticking to your calorie-controlled nutrition plan more achievable with a lower risk of over-eating or binging.

Improve Focus & Mood While Dieting

Along with its effects on your hunger levels and brain chemistry, being in a consistent calorie deficit can also create a “brain-fog”. A lack of concentration, poor memory or feeling flat are all common whilst dieting. ProBurn Advanced’s ingredients will help to clear brain-fog, improve your mood and boost cognitive function.

How to take ProBurn Advanced:

Take 1 capsule of ProBurn Advanced first thing in the morning on an empty stomach with 250-500ml of water. Take another capsule before lunch or training with 250-500ml of water, no later than 5pm. We recommend taking ProALCAR+ at the same time as your ProBurn. Avoid eating other foods or drinking a protein shake within 30 mins after consuming ProBurn. Drink at least 3 litres of water spread evenly throughout the day while using ProBurn Advanced.

ProBurn Advanced Ingredients:

Ingredients: USP BP Caffeine Anhydrous, Alpha-glycerophosphocholine 50%, Green Tea Extract (40% EGCG), 5-HTP (Grionia Simplicifolia Seed Extract), N, N-Dimethyltyramine, Higenamine HCL, Citrus Aurantium Extract (60% Synephrine), Piper Nigrum Extract 4:1, Cayenne Pepper Extract 10:1. Capsules Contain Gelatin. Packaged in Australia from local and imported ingredients.

WARNING: Do not take ProBurn Advanced in excess of its recommended dosage. ProBurn Advanced is intended only for adults over 18. Consult a licensed health- care practitioner before use. Do not use if you are pregnant, nursing or if you have a family history of heart disease, high blood pressure, stroke or any other disease, or using a prescription drug, or over-the-counter drug. Do not consume ProBurn Advanced with any other caffeine products (coffee, tea, soda, etc.). If you are a competitive athlete and/or subject to drug testing, consult with your sanctioning body prior to use to ensure compliance. Discontinue use immediately if you experience any adverse reactions. KEEP OUT OF REACH OF CHILDREN

ProBurn Advanced References:

Caffeine

• The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials. | https://www.ncbi.nlm.nih.gov/pubmed/30335479 |Overall, the current meta-analysis demonstrated that caffeine intake might promote weight, BMI and body fat reduction.
• Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation. | https://www.ncbi.nlm.nih.gov/pubmed/16076989 |High caffeine intake was associated with weight loss through thermogenesis and fat oxidation.
• Caffeine (1, 3, 7-trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters. | https://www.ncbi.nlm.nih.gov/pubmed/20492310 | Caffeine has also been recently linked to weight loss and consequent reduction of the overall risks for developing the metabolic syndrome.
• Caffeine intake is related to successful weight loss maintenance. | https://www.ncbi.nlm.nih.gov/pubmed/26554757 |Consumption of caffeinated beverages might support weight loss maintenance. 

Green Tea Extract

• Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase. | https://www.ncbi.nlm.nih.gov/pubmed/17201629 | Reports have shown that green tea extract intake is associated with increased weight loss due to diet-induced thermogenesis, which is generally attributed to the catechin epigallocatechin gallate. That catechin-polyphenols are known to be capable of inhibiting catechol-O-methyltransferase (the enzyme that degrades norepinephrine) is a possible explanation for why the green tea extract is effective in stimulating thermogenesis by epigallocatechin gallate to augment and prolong sympathetic stimulation of thermogenesis.
• Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. | https://www.ncbi.nlm.nih.gov/pubmed/10702779 | Synergistic interaction between Green tea Catechin-Polyphenols and caffeine to augment and prolong sympathetic stimulation of thermogenesis could be of value in assisting the management of obesity.
• Antiobesity effects of green tea catechins: a mechanistic review. | https://www.ncbi.nlm.nih.gov/pubmed/21115335 |Results from a number of randomized, controlled intervention trials have shown that consumption of Green Tea Catechins (270 mg to 1200 mg/day) may reduce body weight and fat.

Synephrine

• The Effects of Supplementation with p-Synephrine Alone and in Combination with Caffeine on Metabolic, Lipolytic, and Cardiovascular Responses during Resistance Exercise. | https://www.ncbi.nlm.nih.gov/pubmed/27484437 |Supplementation with Synephrine and Synephrine+Caffeine increases lipolysis primarily at rest and increases VO2, EE, and fat oxidation rates 30 minutes following RE. No Heart Rate changes were observed unless caffeine was added.
• Safety, Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p-Synephrine. | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655712/ | No adverse effects were observed or reported with respect to p‐synephrine consumption in the presence or absence of caffeine, while p‐synephrine increased desirable effects including lipolysis, energy expenditure, fat oxidation
• Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. | https://www.ncbi.nlm.nih.gov/pubmed/21537493 | The group receiving p-synephrine (50 mg) alone exhibited a 65 kcal increase in RMR as compared to the placebo group. 

Hordenine

• Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. | https://www.ncbi.nlm.nih.gov/pubmed/2570842 |Therefore, it appears that hordenine acted as an inhibitor of noradrenaline uptake.

5-HTP

• 5-Hydroxytryptophan: A Clinically-Effective Serotonin Precursor | http://www.altmedrev.com/archive/publications/3/4/271.pdf |5-htp crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin. In the CNS, serotonin levels have been implicated in the regulation of sleep, depression, anxiety, appetite.
  Serotonin reciprocally regulates melanocortin neurons to modulate food intake. | https://www.cell.com/neuron/fulltext/S0896-6273(06)00457-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627306004570%3Fshowall%3Dtrue |Serotonin (5-hydroxytryptamine, 5-HT) analogs have been widely developed as weight-loss agents, based largely on early observations of the strong inverse relationship between 5-HT levels and food consumption
• Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation containing 5HTP. | https://www.ncbi.nlm.nih.gov/pubmed/19752879 | All these findings suggest that 5HTP-Nat Exts may be safely used to treat the problem of appetite control in overweight women during a weight loss program.

Alpha-GPC

• Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096089/ |Choline supplementation in female taekwondo and judo athletes can improve lipid metabolism and be used as an antioxidant, as well as encourage rapid body mass reduction.
• The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252552/ |In this community-based population of nondemented individuals, higher concurrent choline intake was related to better cognitive performance.
• Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. | https://www.ncbi.nlm.nih.gov/pubmed/22717142 |Compared with low concentrations, high choline was associated with better test scores in the Train marking test. Low plasma free choline concentrations are associated with poor cognitive performance.
• Effects of CDP-choline on striatal dopamine level and behavior in rats. | https://www.ncbi.nlm.nih.gov/pubmed/7253343 |CDP-choline (300 mg/kg, i.p.) increased the DA content in the striatum (p less than 0.05) one hour after injection.

Capsaicin

• Acute effects of capsaicin on energy expenditure and fat oxidation in negative energy balance. | https://www.ncbi.nlm.nih.gov/pubmed/23844093 |Consumption of 2.56 mg capsaicin per meal promotes fat oxidation in negative energy balance
• Combined medium-chain triglyceride and chilli feeding increases diet-induced thermogenesis in normal-weight humans. | https://www.ncbi.nlm.nih.gov/pubmed/23179202 | Adding chilli and MCT to meals increases Diet Induced Thermogenesis by over 50 % which over time may cumulate to help induce weight loss and prevent weight gain or regain.
• Effects of red pepper on appetite and energy intake. | https://www.ncbi.nlm.nih.gov/pubmed/10743483 | Results indicate that the ingestion of red pepper decreases appetite and subsequent protein and fat intakes in Japanese females and energy intake in Caucasian males. Moreover, this effect might be related to an increase in sympathetic nervous system activity in Caucasian males.
• The effects of capsaicin and capsiate on energy balance: critical review and meta-analyses of studies in humans. | https://www.ncbi.nlm.nih.gov/pubmed/22038945 |
• Evidence indicates that capsaicin and capsiate both augment energy expenditure and enhance fat oxidation, especially at high doses. Furthermore, the balance of the literature suggests that capsaicin and capsiate suppress orexigenic sensations. 
• Sensory and gastrointestinal satiety effects of capsaicin on food intake | https://www.ncbi.nlm.nih.gov/pubmed/15611784 |Both oral and gastrointestinal exposure to capsaicin increased satiety and reduced energy and fat intake; the stronger reduction with oral exposure suggests a sensory effect of capsaicin.